Collaborative Computational Project
for Electron cryo-Microscopy

MRC

Icknield Workshop: Model Building and Refinement using cryo-EM Maps

Course kindly hosted at RAL by DLS | April 2019

Schedule

Schedule

Lectures

CCP-EM: Tom Burnley

Introduction

LocScale: Arjen Jakobi

Map sharpening tools for cryo-EM density maps

Buccaneer: Kevin Cowtan

Model building in Buccaneer and Nautilus

MolProbity: Jane Richardson

Validating CryoEM models from diagnosis to healing

ARP/wARP: Grzegorz Chojnowski

Model building into high resolution cryo-EM maps

Coot: Paul Emsley

Cryo-EM Model-Building with Modern Coot

Refmac: Garib Murshudov

Refinement against cryo-EM maps

Refmac: Rob Nicholls

Restraints in Cryo-EM Refinement

Refmac: Rangana Warshamanage

Correlation as a measure of validation in cryoEM

Flex-EM & TEMPy: Agnel Joseph

TBC

ISOLDE: Tristan Croll

Isolde: Bringing macromolecular model building to life

EMDB: Osman Salih

TBC

Tutorials

CCP-EM: Buccaneer, Refmac, LocScale

Buccaneer tutorial and data

Refmac tutorial and data

LocScale tutorial and data

Prepare map for LocScale script

Coot

Coot Cryo-EM Basics

Coot Cryo-EM Main